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Index > Protein center > Pla2g6(Gene name) > Rat
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  • Pla2g6 (Gene name),
  • 85/88 kDa calcium-independent phospholipase A2 (Protein name ),  PLPL9_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Pla2g6(Pnpla9);
    Protein name:
    85/88 kDa calcium-independent phospholipase A2(CaI-PLA2);
    Alternative:
    Intracellular membrane-associated calcium-independent phospholipase A2 beta(iPLA2-beta);Group VI phospholipase A2(GVI PLA2);Patatin-like phospholipase domain-containing protein 9(PNPLA9);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
    Subcellular Location:
    Isoform Short Cytoplasm
    Protein Attributes:
    Sequence length:
    807
    Sequence:
    50:
    MQFFGRLVNT | LSSVTNLFSN | PFRVKEVSLA | DYASSERVRE | EGQLILLQNA | 
    100:
    SNRTWDCVLV | SPRNPQSGFR | LFQLESEADA | LVNFQQYSSQ | LPPFYESSVQ | 
    150:
    VLHVEVLQHL | TDLIRNHPSW | TVTHLAVELG | IRECFHHSRI | ISCANSTENE | 
    200:
    EGCTPLHLAC | RKGDSEILVE | LVQYCHAQMD | VTDNKGETAF | HYAVQGDNPQ | 
    250:
    VLQLLGKNAS | AGLNQVNNQG | LTPLHLACQM | GKQEMVRVLL | LCNARCNIMG | 
    300:
    PGGFPIHTAM | KFSQKGCAEM | IISMDSNQIH | SKDPRYGASP | LHWAKNAEMA | 
    350:
    RMLLKRGCDV | DSTSASGNTA | LHVAVTRNRF | DCVMVLLTYG | ANAGARGEHG | 
    400:
    NTPLHLAMSK | DNMEMVKALI | VFGAEVDTPN | DFGETPAFIA | SKISKLITRK | 
    450:
    ALLTLLKTVG | ADYHFPFIQG | VSTEQSSAAG | PHPFFSLDRT | QPPTISLNNL | 
    500:
    ELQDLMPVSR | ARKPAFILSS | MRDEKRSHDH | LLCLDGGGVK | GLVIIQLLIA | 
    550:
    IEKASGVATK | DLFDWVAGTS | TGGILALAIL | HSKSMAYMRG | VYFRMKDEVF | 
    600:
    RGSRPYESGP | LEEFLKREFG | EHTKMTDVKK | PKVMLTGTLS | DRQPAELHLF | 
    650:
    RNYDAPEAVR | EPRCTPNINL | KPPTQPADQL | VWRAARSSGA | APTYFRPNGR | 
    700:
    FLDGGLLANN | PTLDAMTEIH | EYNQDMIRKG | QGNKVKKLSI | VVSLGTGKSP | 
    750:
    QVPVTCVDVF | RPSNPWELAK | TVFGAKELGK | MVVDCCTDPD | GRAVDRARAW | 
    800:
    CEMVGIQYFR | LNPQLGSDIM | LDEVSDAVLV | NALWETEVYI | YEHREEFQKL | 
    807:
    VQLLLSP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat CaI-PLA2
    Cat.:
    E0411r
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    Packing:
    96T
    ELISA Kit for Rat CaI-PLA2
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    E0411h
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    Packing:
    96T
    ELISA Kit for Rat CaI-PLA2
    Cat.:
    E0411m
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    Packing:
    96T
    CLIA Kit for Rat CaI-PLA2
    Cat.:
    U0411m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat CaI-PLA2
    Cat.:
    U0411r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat CaI-PLA2
    Cat.:
    U0411h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat CaI-PLA2
    Cat.:
    P0411Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CaI-PLA2
    Cat.:
    P0411Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat CaI-PLA2
    Cat.:
    P0411Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat CaI-PLA2
    Monoclonal Antibody for Rat CaI-PLA2
    Monoclonal Antibody for Rat CaI-PLA2
    Protein for Rat CaI-PLA2
    Protein for Rat CaI-PLA2
    Protein for Rat CaI-PLA2

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    Linearity
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    References
    1. 1.
      "Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural homologous to the integral membrane protein binding domain of ankyrin."
      Ma Z. , Ramanadham S. , Kempe K. , Chi X.S. , Ladenson J. , Turk J.
      J. Biol. Chem.272:11118-11127(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
      strain: Sprague-Dawley.
      tissue: Pancreatic islet.
    2. 2.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG)
      tissue: Testis.
    5. 5.
      "Identification of the calmodulin-binding domain of recombinant calcium-independent phospholipase A2beta. implications for structure and function."
      Jenkins C.M. , Wolf M.J. , Mancuso D.J. , Gross R.W.
      J. Biol. Chem.276:7129-7135(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;CALMODULIN-BINDING REGIONS
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